Ethyl 2-(3-amino-4-hydroxyphenyl)acetate
نویسندگان
چکیده
The asymmetric unit of the title compound, C(10)H(13)NO(3), contains two crystallographically independent mol-ecules with different conformations of the eth-oxy-carbonyl groups; the terminal C-C-O-C torsion angles in the two mol-ecules are 83.6 (6) and -171.1 (3)°, resulting in twisted and straight chain conformations, respectively. The crystal structure is stabilized by inter-molecular N-H⋯O, O-H⋯N and C-H⋯O hydrogen bonds. Intra-molecular hydrogen bonds occur between the amino N and phenolic O atoms.
منابع مشابه
Condensation reactions of 3-oxo-2-arylhydrazonopropanals with active methylene reagents: formation of 2-hydroxy- and 2-amino-6-substituted-5-arylazonicotinates and pyrido[3,2-c]cinnolines via 6π-electrocyclization reactions.
3-Oxo-3-phenyl-2-(p-tolylhydrazono)propanal (1a) undergoes condensation with ethyl cyanoacetate in acetic acid in the presence of ammonium acetate to yield either 2-hydroxy-6-phenyl-5-p-tolylazonicotinic acid ethyl ester (6a) or 2-amino-6-phenyl-5-ptolyl-azonicotinic acid ethyl ester (8), depending on the reaction conditions. Similarly, other 3-oxo-3-aryl-2-arylhydrazonopropanals 1a,b condense ...
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The title compound, C(22)H(32)N(2)O(2)S, was obtained by dehydroxy-lation and deacetyl-ation of 4-{(1S,2S)-2-(benzylhydroxy-amino)-3-methyl-1-[(S)-2-methyl-propane-2-sulfinylamino]but-yl}phenyl acetate, which was derived from reductive crosslinking of nitrone with N-tert-butane-sulfinyl-imine. The crystal structure shows that the mol-ecules are linked by O-H⋯O hydrogen bonds.
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The title compound, C17H15N5O4, was obtained via the condensation of 3-eth-oxy-2-[2-(4-nitro-phen-yl)hydrazono]-3-oxo-propanoic acid with 1,2-di-amino-benzene. In the mol-ecule, the dihedral angles between the acetate group and the two aromatic subunits (benzimidazole and nitro-phenyl-hydrazone) are 7.35 (9) and 18.23 (9)°, respectively. Intra-molecular N-H⋯O and N-H⋯N contacts occur. In the cr...
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